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Georgios Pampalakis Selected Research

Netherton Syndrome

1/2022Cocktails of KLK5 Protease Inhibitors and Anti-TNFα Therapeutics: an Effective Treatment for Netherton Syndrome.
7/2021A novel theranostic activity-based probe targeting kallikrein 7 for the diagnosis and treatment of skin diseases.
1/2021Generation of a quenched phosphonate activity-based probe for labelling the active KLK7 protease.
10/2020Cathelicidin represents a new target for manipulation of skin inflammation in Netherton syndrome.
7/2019A proinflammatory role of KLK6 protease in Netherton syndrome.
1/2019Activography reveals aberrant proteolysis in desquamating diseases of differing backgrounds.

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Georgios Pampalakis Research Topics

Disease

26Neoplasms (Cancer)
11/2021 - 07/2002
8Ovarian Neoplasms (Ovarian Cancer)
11/2015 - 07/2002
6Netherton Syndrome
01/2022 - 01/2019
6Breast Neoplasms (Breast Cancer)
11/2019 - 06/2006
6Prostatic Neoplasms (Prostate Cancer)
11/2010 - 11/2005
4Inflammation (Inflammations)
11/2021 - 09/2015
3Ichthyosis (Xeroderma)
01/2022 - 01/2019
3Skin Diseases (Skin Disease)
07/2021 - 01/2021
3Neoplasm Metastasis (Metastasis)
11/2019 - 01/2014
3Carcinogenesis
10/2019 - 11/2015
3Parkinson Disease (Parkinson's Disease)
02/2017 - 07/2002
3Alzheimer Disease (Alzheimer's Disease)
04/2012 - 07/2002
2Psoriasis (Pustulosis Palmaris et Plantaris)
01/2022 - 09/2007
2Melanoma (Melanoma, Malignant)
01/2021 - 12/2018
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2019 - 01/2018
1Human Influenza (Influenza)
11/2021
1Virus Diseases (Viral Diseases)
11/2021
1Infections
11/2021
1Atopic Dermatitis (Atopic Eczema)
01/2021
1Cicatrix (Scar)
01/2021
1Dandruff
01/2020
1Colonic Neoplasms (Colon Cancer)
10/2019
1Colorectal Neoplasms (Colorectal Cancer)
10/2019
1Disease Progression
01/2019
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
12/2018
1Skin Neoplasms (Skin Cancer)
12/2018
1Vaginal Neoplasms (Cancer, Vaginal)
01/2018
1Synucleinopathies
02/2017
1acral type Peeling skin syndrome
01/2017
1Starvation
05/2014
1Demyelinating Diseases (Demyelinating Disease)
12/2012
1Multiple Sclerosis
12/2012
1Asthma (Bronchial Asthma)
12/2012
1Neurodegenerative Diseases (Neurodegenerative Disease)
04/2012
1Amyloid Plaque
08/2011
1Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
05/2009
1Hyperplasia
05/2008

Drug/Important Bio-Agent (IBA)

23Kallikreins (Kallikrein)IBA
11/2021 - 07/2002
17Peptide Hydrolases (Proteases)FDA Link
11/2021 - 07/2002
10Serine Proteases (Serine Protease)IBA
01/2021 - 07/2002
10Biomarkers (Surrogate Marker)IBA
11/2019 - 07/2004
7Proteins (Proteins, Gene)FDA Link
01/2022 - 07/2002
5EnzymesIBA
11/2021 - 02/2010
5MicroRNAs (MicroRNA)IBA
10/2019 - 08/2009
4Tumor Biomarkers (Tumor Markers)IBA
10/2009 - 07/2002
3Pharmaceutical PreparationsIBA
11/2021 - 06/2006
3Complementary DNA (cDNA)IBA
01/2021 - 05/2009
3RNA (Ribonucleic Acid)IBA
01/2021 - 02/2010
3Messenger RNA (mRNA)IBA
05/2011 - 10/2009
3Prostate-Specific Antigen (Semenogelase)IBA
11/2010 - 09/2007
3Tissue Kallikreins (Tissue Kallikrein)IBA
09/2007 - 05/2006
2Phenobarbital (Luminal)FDA Link
10/2019 - 01/2014
2LipidsIBA
01/2019 - 11/2015
2anthraceneIBA
12/2018 - 01/2018
2SynucleinsIBA
02/2017 - 07/2014
2CholesterolIBA
11/2015 - 05/2014
2Biological ProductsIBA
01/2014 - 10/2009
2Amyloid (Amyloid Fibrils)IBA
08/2011 - 07/2002
2ChromatinIBA
05/2009 - 06/2006
2DecitabineFDA Link
06/2006 - 06/2006
1involucrinIBA
01/2022
1loricrinIBA
01/2022
1Protease Inhibitors (Protease Inhibitor)IBA
01/2022
1Hemagglutinins (Hemagglutinin)IBA
11/2021
1CosmeceuticalsIBA
01/2021
1ChymotrypsinFDA Link
01/2021
1CathelicidinsIBA
10/2020
1Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA
10/2020
1AgarIBA
11/2019
1Keratins (Keratin)IBA
11/2019
1S100 Proteins (S 100 Protein)IBA
11/2019
1CateninsIBA
11/2019
1Transcription Factors (Transcription Factor)IBA
10/2019
1RNA-Binding Proteins (RNA-Binding Protein)IBA
10/2019
1CytokinesIBA
12/2018
1transglutaminase 5IBA
01/2017
1geranylgeranyl pyrophosphate (geranylgeranyl diphosphate)IBA
05/2014
1Mevalonic Acid (Mevalonate)IBA
05/2014
1AntibodiesIBA
12/2012
1ProdrugsIBA
12/2012
1LigandsIBA
08/2011
1Liposomes (Liposome)IBA
08/2011
1Netrin-1IBA
05/2011
1DCC ReceptorIBA
05/2011
1Nucleic AcidsIBA
10/2009
1Cell ExtractsIBA
10/2009
1VimentinIBA
05/2009
1CalreticulinIBA
05/2009
1Methyl-CpG-Binding Protein 2IBA
05/2009
1Histones (Histone)IBA
05/2009
1Keratin-8 (Keratin 8)IBA
05/2009
1Protein Isoforms (Isoforms)IBA
05/2008
1FibrinolysinFDA Link
09/2007
1Hormones (Hormone)IBA
09/2007
1seocalcitolIBA
06/2006
1Cholecalciferol (Vitamin D3)FDA Link
06/2006
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
06/2006

Therapy/Procedure

3Therapeutics
01/2022 - 08/2009
1Precision Medicine
07/2021
1Microelectrodes
10/2009